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Cybernetics is not just another branch of science. It is an intellectual revolution that rivals in importance the earlier Industrial Revolution.
Isacc Asimov, 1950
Open Problems in Artificial Life
Mark A. Bedau¤;†, John S. McCaskill‡, Norman H. Packard§, Steen Rasmussen¤¤, Chris Adami††, David G. Green‡‡, Takashi Ikegami§§, Kunihiko Kaneko¤¤¤, Thomas S. Ray†††
Abstract This article lists fourteen open problems in artificial life, each of which is a grand challenge requiring a major advance on a fundamental issue for its solution. Each problem is briefly explained, and, where deemed helpful, some promising paths to its solution are indicated.
A List of Open Problems
A. How does life arise from the nonliving?
1. Generate a molecular proto-organism in vitro.
2. Achieve the transition to life in an artificial chemistry in silico.
3. Determine whether fundamentally novel living organizations can exist.
4. Simulate a unicellular organism over its entire lifecycle.
5. Explain how rules and symbols are generated from physical dynamics in
living systems.
B. What are the potentials and limits of living systems?
6. Determine what is inevitable in the open-ended evolution of life.
7. Determine minimal conditions for evolutionary transitions from specific to
generic response systems.
8. Create a formal framework for synthesizing dynamical hierarchies at all scales.
9. Determine the predictability of evolutionary consequences of manipulating
organisms and ecosystems.
10. Develop a theory of information processing, information flow, and
information generation for evolving systems.
C. How is life related to mind, machines, and culture?
11. Demonstrate the emergence of intelligence and mind in an artificial living
system.
12. Evaluate the influence of machines on the next major evolutionary transition
of life.
13. Provide a quantitative model of the interplay between cultural and biological
evolution.
14. Establish ethical principles for artificial life.
Mark A. Bedau is an American philosopher who works in the field of Artificial Life. He is the son of philosopher Hugo Adam Bedau.
Bedau teaches philosophy at Reed College. He is also the Co-Founder of the European Center for Living Technology (ECLT)[1] and Visiting Professor, Ph.D. Program in Life Sciences: Foundations and Ethics, European School of Molecular Medicine.[2] Bedau is also the editor of the Artificial Life Journal.[3] He has been the COO of Protolife, a biotechnology start-up based in Venice, Italy.
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EmTech: Get Ready for a New Human Species
Now that we can rewrite the code of life, Darwinian evolution can't stop us, says investor Juan Enriquez., Wednesday, October 19, 2011By Emily Singer
The ability to engineer life is going to spark a revolution that will dwarf the industrial and digital revolutions, says Juan Enriquez, a writer, investor, and managing director of Excel Venture Management. Thanks to new genomics technologies, scientists have not only been able to read organisms' genomes faster than ever before, they can also write increasingly complex changes into those genomes, creating organisms with new capabilities.
Enriquez, who spoke at Technology Review's EmTech conference on Tuesday, says our newfound ability to write the code of life will profoundly change the world as we know it. Because we can engineer our environment and ourselves, humanity is moving beyond the constraints of Darwinian evolution. The result, he says, may be an entirely new species.
Enriquez is the author of the global bestseller As the Future Catches You: How Genomics & Other Forces Are Changing Your Life, Work, Health & Wealth. His most recent publication is an eBook, Homo Evolutis: A Short Tour of Our New Species.
Technology Review senior editor Emily Singer spoke with Enriquez after his talk.
TR: Why do you think there is going to be a new human species?
Juan Enriquez: The new human species is one that begins to engineer the evolution of viruses, plants, animals, and itself. As we do that, Darwin's rules get significantly bent, and sometimes even broken. By taking direct and deliberate control over our evolution, we are living in a world where we are modifying stuff according to our desires.
If you turned off the electricity in the United States, you would see millions of people die quickly, because they wouldn't have asthma medications, respirators, insulin, a whole host of things we invented to prevent people from dying. Eventually, we get to the point where evolution is guided by what we're engineering. That's a big deal. Today's plastic surgery is going to seem tame compared to what's coming.
How is this impending revolution going to shape the world?
Ninety-eight percent of data transmitted today is in a language almost no one spoke 30 years ago. We're in a similar period now. But this revolution will be more widespread because this is software that writes its own hardware.
People think this technology will just change pharma or biotech, but it's much bigger than that. For example, it's already changing the chemical industry. Forty percent of Dupont's earnings today come from the life sciences. It's going to change everything; it will change countries, who's rich and who's poor. It's going to create new ethics.
New ethics?
It will change even basic questions like sex. There used to be one way to have a baby. Now there are at least 17. We have decoupled sex from time. You can have a baby in nine months, or you can freeze sperm or a fertilized egg and implant it in 10 years or 100 years. You can create an animal from one of its cells. You can begin to alter reproductive cells. By the time you put this together, you've fundamentally changed how you reproduce and the rules for reproduction.
What does it take to make a new species?
We're beginning to see that it's an accumulation of small changes. Scientists have recently been able to compare the genomes of Neandertals and modern humans, which reveals just a .004 percent difference. Most of those changes lie in genes involved in sperm, testes, smell, and skin.
Engineering microbes alone might speciate us. When you apply sequencing technology to the microbes inhabiting the human body, it turns out to be fascinating. All of us are symbionts; we have 1,000 times more microbial cells in our bodies than human cells. You couldn't possible digest or live without the microbial cells inside your stomach. Some people have microbes that are better at absorbing calories. Diabetics have a slightly sweeter skin, which changes the microbial fauna and makes it harder for them to cauterize wounds.
One concern about human enhancement is that only some people will have access, creating an even greater economic divide. Do you think this will be the case?
In the industrial revolution, it took a lifetime to build enough industry to double the wealth of a country. In the knowledge revolution, you can build billion-dollar companies with 20 people very quickly. The implication is that you can double the wealth of a country very quickly. In Korea in 1975, people had one-fifth of the income of Mexicans, and today they have five times more. Even the poorest places can generate wealth quickly. You see this in Bangalore, China. On the flip side, you can also become irrelevant very quickly.
Scientists are on the verge of sequencing 10,000 human genomes. You point out this might highlight significant variation among our species, and that this requires some ethical consideration. Why?
The issue of [genetic variation] is a really uncomfortable question, one that for good reason, we have been avoiding since the 1930s and '40s. A lot of the research behind the eugenics movement came out of elite universities in the U.S. It was disastrously misapplied. But you do have to ask, if there are fundamental differences in species like dogs and horses and birds, is it true that there are no significant differences between humans? We are going to have an answer to that question very quickly. If we do, we need to think through an ethical, moral framework to think about questions that go way beyond science.
Avots: http://www.technologyreview.com/biomedicine/38932/?nlid=nldly&nld=2011-10-19
Researchers Mimic Nature to Create a 'Bio-Inspired Brain' for Robots
ScienceDaily (July 27, 2011) — A group of engineers at NUI Galway and the University of Ulster is developing bio-inspired integrated circuit technology which mimics the neuron structure and operation of the brain. One key goal of the research is the application of the electronic neural device, called a hardware spiking neural network, to the control of autonomous robots which can operate independently in remote, unsupervised environments, such as remote search and rescue applications, and in space exploration.
One key goal of the research is the application of the electronic neural device, called a hardware spiking neural network, to the control of autonomous robots which can operate independently in remote, unsupervised environments, such as remote search and rescue applications, and in space exploration.
According to Dr Fearghal Morgan, Director of the Bio-Inspired Electronics and Reconfigurable Computing (BIRC) research group, at NUI Galway: "Electronic neurons, implemented using silicon integrated circuit technology, cannot exactly replicate the complexity of neurons found in the human brain, or the massive number of connections between neurons.
"However, inspired by the operation and structure of the brain, we have successfully developed a hardware spiking neural network and have used this device for robotics control. The electronic device interprets the state of the robot's environment through signals received from sensing devices such as cameras and ultrasonic sensors, which act as the eyes and ears of the robot.
"The neural network then modifies the behaviour of the robot accordingly, by sending signals to the robot's limbs to enable activity such as walking, grasping and obstacle avoidance." Dr Morgan explains: "Our research is focussed on mimicking evolution in nature. The latest hardware neural network currently in development will contain thousands of small electronic neuron-like devices which interoperate concurrently, in a similar way to neurons in the biological brain. The device can be trained to perform a particular function, and can be retrained many times for various applications.
"The training process resembles the training of the brain, by making, strengthening and weakening the links between neurons and defining the conditions which cause a neuron to fire, sending signals to all of the attached neurons. As in the brain, the collection of interconnected neurons makes decisions on incoming data to cause an action in the controlled system.
"Until now, the robotics arena has focused on electronic controllers which incorporate one or more microprocessors, which typically execute instructions in sequence and, while performing tasks quickly, are limited by the instruction processing speed. Power is also a consideration. While the human brain on average only requires 10 watts of power, a typical PC requires 300 watts.
"We believe that a small embedded hardware neural network device has the potential to perform effective robotics control, at low power, while also incorporating fault detection and self-repair behaviour. Our aim is to develop a robust, intelligent hardware neural network robotics controller which can autonomously maintain robot behaviour, even when its environment changes or a fault occurs within the robotics system."
Dr Jim Harkin, from the School of Computing and Intelligent Systems at the University of Ulster's Magee campus), said: "The constant miniaturisation of silicon technology to increase performance introduces inherent reliability issues which must be overcome. Ultimately, the hardware neural network or robot 'brain' will be able to detect and overcome electronic faults that occur within itself, and continue to function effectively without human intervention."